The purpose of this study was to investigate the effect of ownership structure factors and some of the mechanisms of corporate governance on the manipulation of listed companies in Tehran Stock Exchange. To test the hypotheses of the research, regression analysis and correlation test have been used. For this research, 74 companies that have been admitted to the Stock Exchange for the period of eight years from 1387 to 1394 have been used in two cross-sectional and cumulative formats. The results of this research show that when the percentage of institutional investors' ownership in companies exceeds 45%, manipulation is reduced by management. In addition, the research findings indicate that there is a negative and significant relationship between audit quality and profit manipulation. Also, the findings of this research show that there is no significant relationship between the existence of non-executive directors in the composition of the board of directors and the existence of internal auditors and manipulation by management.